Transcriptomics Maximal force Gene editing Autophagy Mouse model Myotonic Dystrophy Type 1 Genotype phenotype correlation KNOCKOUT MICE Heart failure AAV Myostatin Cultured DM1 Myelin DMSXL mice Myotonic Dystrophy Glucocorticoids Duchenne muscular dystrophy Male PCR Thérapie génique CMS Dystrophin Hypoxia Transgenic mouse model Motoneuron Myotonic Dystrophy type 1 GSK3␤ Myotonic dystrophy Quantitative microdialysis Trinucleotide Repeat Expansion Exercice Astrocyte Aging Cardiac muscle PacBio Antisense oligonucleotide Desmin Cell model Muscular dystrophy Dynamin 2 Exercise RNA biology DMPK Acute coronary syndrome Cell penetrating peptide Acetylcholinesterase deficiency ACETYLCHOLINESTERASE Neuron Myotonic dystrophy mouse models Therapy Dilated cardiomyopathy Fibrosis Acetylcholinesterase knockout mouse Oligodendrocytes Gene therapy Glial cells CTG repeat instability CRISPR/Cas9 Glucocorticoid-receptor Alternative splicing Brain dysfunction Dystrophie myotonique CTG repeats Astrocytes Brain ARN BIOLOGIE MOLECULAIRE Cytoskeleton MBNL CRISPRi Myotonic dystrophy type 1 Oligodendrocyte Expression CTG repeat contractions Humans GABA Gene Therapy Cell culture model Muscle Endurance training Centronuclear myopathy Mice Diaphragm Antisense oligonucleotides Mouse models Glutamate RNA splicing Dystrophie Myotonique Heart Skeletal muscle Intermediate filament CONGENITAL MYATHENIC SYNDROME Transgenic mouse Animals Trinucleotide repeat expansion Central nervous system Cells Long read sequencing RNA interference