This study assesses inputs use efficiency of durum wheat farmers, subscribed under a common Agricultural Decision Support System (ADSS), especially designed by Barilla and HORTA for this cultivation. Data Envelopment Analysis was the main analysis used to highlight differences in the implementation stage of ADSS’s suggestions, between 4 agricultural firms (2 Italian and 2 Greek) (N= 563 farmers). By incorporating economic (variable costs) and environmental factors (Carbon, Water and Environmental footprints), performance differences between farms both on regional and national level arose. Lastly, closer monitoring for clarifying the reasoning of the obtained differences in the implementation stage is proposed.